Drug shortages keep on growing. Older, injectable medicines are among the most vulnerable

Drug shortages keep on growing. Older, injectable medicines are among the most vulnerable

Drug shortages keep on growing. Older, injectable medicines are among the most vulnerable

Erin Fox has tracked drug shortages for more than 20 years, and she sees no easy solutions for what has become a record run

ByTOM MURPHY AP health writer

June 17, 2024, 9:54 AM

    Erin Fox has tracked drug shortages for more than 20 years, and she sees no easy solutions for what has become a record run.

    Total active shortages hit an all-time high of 323 in this year’s first quarter, according to the University of Utah Drug Information Service. That’s up about 86% from a 10-year low of 174 last reached in 2017.

    There were 48 new shortages recorded this year through March, according to the data, published by the American Society of Health-System Pharmacists.

    Still, Fox also sees positive news developing. The associate chief pharmacy officer at University of Utah Health spoke recently with The Associated Press. The conversation has been edited for clarity and length.

    A: Unfortunately, no. We haven’t necessarily solved some of the root causes.

    We have, overall, relatively few manufacturers. (The U.S. Food and Drug Administration) halted inspections during COVID. Now they’re back, at factories that maybe haven’t been inspected for five or six years. They’re finding some things to fix. Those fixes can take anywhere from 6 to 18 months for production to get fully back on schedule.

    Meanwhile, other companies don’t necessarily have the capacity to ramp up production to make up the difference.

    It’s not the FDA’s fault. We want them to find those quality deficits. But when FDA goes out looking all at once, it can be pretty disruptive.

    A: Generic, injectable hospital drugs or older drugs. They are usually pretty low cost. There’s not a lot of resilience in the supply chain for another company to make up the difference.

    We saw all those chemotherapy shortages last year in part because a large factory in India, (the FDA) found quality problems there. They made a large amount of the U.S. supply. The other companies were unable to quickly make up the difference.

    Things have definitely improved, but that factory is still not running.

    A: They shouldn’t automatically assume they won’t be able to get that treatment.

    It might be delayed or they might have to take a capsule instead of a pill. They might have to call their insurance company to ask if they will cover the brand because sometimes (that) is available while the generic is not.

    Don’t panic. It’s frustrating to have to do a little bit of work, but usually you will still be able to get a treatment.

    A: Last year, Congress held four hearings on shortages. They’re still very interested. People are really starting to talk about doing hard work both on the policy side but also maybe a little bit of Congressional action to really try to move this problem forward.

    I’ve been leading our efforts to provide data on drug shortages since 2001. This is truly the most interest I’ve ever seen.

    ___

    The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.

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